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Sentence examples for modulating the microenvironment from inspiring English sources

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In this brief review, we have assembled evidence describing several distinct functions for extracellular vesicles in modulating the microenvironment with examples that include immune evasion, angiogenesis and stromal activation.

Recently, studies have demonstrated that modulating the microenvironment in LSEC cultures can delay the dedifferentiation of LSECs [23] [25].

In corollary, approaches targeting tumor angiogenesis represent an exciting option in anti-cancer therapy through modulating the microenvironment [ 31].

Exosomes may transfer unique patterns of their contents to neighboring cells and may therefore induce the phenotypic modifications in recipient cells, subsequently modulating the microenvironment [ 37, 38].

Few other combination approaches were suggested such as conditioning of MSCs with the drugs such as bortezomib by modulating the microenvironment and thereby enhancing the therapeutic efficiency of MSCs [ 33].

In doing so, the authors were able to demonstrate the potential involvement of HO-1 expression in hematopoietic cell compartment in promoting metastatic disease in the lungs through modulating the microenvironment.

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Mesenchymal stem cells are able to transdifferentiate to renal epithelial cells and modulate the microenvironment in endocrine and paracrine ways.

Biomaterials approaches modulate the microenvironment of a regenerating nerve through tailored presentation of signaling molecules, creating physical and biochemical guidance cues to direct axonal regrowth across nerve lesion sites.

Astrocytes are well known to directly influence neuronal survival and modulate the microenvironment of the nervous system by affecting glutamate uptake and release, free radical scavenging, water transport, and production of cytokines, chemokines and nitric oxide [25], [62] [66].

Identifying and blocking the mechanisms with which follicular lymphoma modulates the microenvironment could be of great clinical benefit.

It is reasonable to assume that the mutations close to the histidines modulate the microenvironment and the p Ka of the existing histidines.

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