Sentence examples for modulating the differentiation from inspiring English sources

The influence of the GHA matrix on cell growth and on modulating the differentiation ability of mesenchymal stem cells was evaluated by different biochemical and immunostaining assays.

In summary, this study proved for the first time the potentials of baculovirus in modulating the differentiation status of chondrocytes in the context of cartilage tissue engineering, but also highlighted the importance of selecting appropriate cell passage and growth factor for genetic manipulation.

AST administration counteracted the harmful effect by modulating the differentiation of T cells, increase of anti-oxidant enzymes, and inhibition of neuroinflammation.

Our studies further suggest that modulating the activity of Wnt/β-catenin signalling, through the expression of Fezf2, might provide a powerful means of modulating the differentiation fates of neural stem cells, reprogramming postmitotic neurons or inducing neuronal plasticity.

The emodin prevents bone loss by modulating the differentiation of the osteogenic and adipogenic lineages, as shown in the enhancement of the osteogenic gene expression markers and osteoblast phenotypic characteristics, eventually promoting osteoblastogenesis.

The overall immunologic effects of 1,25(OH)2D include downregulating Th1 immune responses, modulating the differentiation of dendritic cells (DCs), and lowering proliferation of activated B cells, while upregulating regulatory T cells and preserving innate immune responses.,, Each of the immune pathways influenced by 1,25(OhasD has profound potential implications for patients with SLE.

However, whether PCA modulates the differentiation of NS/PCs has remained to be elucidated.

Quiescent HSCs or culture-activated HSCs do not have the ability to modulate the differentiation of MSCs.

The present study investigated the ability of two polymers (pHM1 and pHM3) with different positive surface charge densities to modulate the differentiation of MSCs into osteoblast-like phenotype via cell-cell ephrinB2/EphB4 signaling.

It has been shown that TLRs modulates the differentiation of MSCs [16], [17].

In this study, we hypothesize that corneal wounding may modulate the differentiation of corneal epithelial cells due to a disrupted BM, resulting in de-differentiation of corneal epithelial cells, i.e., the likely progenitor cells of corneal epithelium.