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In summary, nanotopography is capable of modulating cell behavior and influencing the cell-cell interactions of astrocytes.
Polymeric nanofibers display unique mechanical properties, which are useful for modulating cell behavior as well providing adequate strength and tension to the cells seeded into the scaffolds.
The architectural matrix organizes and imparts structural integrity to individual tissues, in addition to modulating cell behavior by interacting with cell surface receptors and soluble growth factors.
Examples of such strategies include biomimicry (e.g., the attachment of phospholipids to coating surfaces), employing naturally derived materials as coatings, utilizing membranes that reduce cell adhesion, encouraging tissue ingrowth into porous coatings, and modulating cell behavior through coating topography.
This review provides insight into emerging degradable and cell-compatible hydrogels for understanding and modulating cell behavior for various bioengineering applications.
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Collectively, these findings suggest that Smo and primary cilia-dependent noncanonical Hh signaling leads to post-translational regulation of microtubules and may be important for modulating cell behaviors.
Vice versa, the ECM exhibits unique mechanical signatures associated with its fibrous polymer network that can modulate cell behavior.
Recent trends in scaffold design have focused on materials that can provide appropriate guidance cues for particular cell types to modulate cell behavior.
Furthermore, the degree of enzymatic crosslinking of the gelatin-Ph hydrogels could be used to modulate cell behavior and the extent of vascular network formation in vivo.
The 3D structures of collagen, a major component of extracellular matrix, might modulate cell behavior, such as osteoblasts in bone formation.
Objective The interactions between integrins and extracellular matrix proteins are known to modulate cell behavior, and may be involved in regulating cartilage formation and repair.
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