Sentence examples for modulating cell cycle from inspiring English sources

Future studies will investigate whether NAP1L3 contributes to cellular transformation or maintenance of AML by modulating cell cycle progression and HOXA, MYC, and E2F gene expression.

The goal of the present study was to investigate the role of SCD1 in modulating cell cycle progression.

In the present work, we provide new evidence that SCD1 controls the rate of cancer cell mitogenesis by modulating cell cycle progression.

It was proposed that µ-calpain cleaves CDKN2D after the R25, H29, Q47, G64, L113 and A127 residues, and plays an important role in modulating cell cycle regulatory protein turnover [27].

JNK has an important role in modulating cell cycle progression.

As is ubiquitously expressed, we speculate that endogenous ouabain has a developmental role in modulating cell cycle progression.

Our previous report revealed that HBXIP accelerated cell proliferation by modulating cell cycle-related proteins (8).

Discovery of the expression and tyrosine phosphorylation of FAK highly correlated with cell cycle progression by modulating cell cycle-relative molecules [ 31] highlights FAK functioning as a key regulator in promoting cancer proliferation.

Constitutively activated STAT3 signalling in tumours has been shown to promote cell-cycle progression and prevent apoptosis by modulating cell cycle-associated and apoptosis-associated proteins such as cyclin D1 and Bcl-2; this is a possible mechanism of resistance to conventional chemotherapy and radiotherapy (Huang, 2007; Al Zaid Siddiquee and Turkson, 2008; Aggarwal et al, 2009).

PRKDC, PARP1, NPM1 and XRCC6 are hepatocellular carcinoma over-expression genes which modulate cell cycle regulation network through the modulation of UBC[ 49].

Sun, H. et al. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway.