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Our data reveal that gene regulatory networks modulated by single modulator or co-modulated by multiple modulators play important roles in breast cancer.
Previous studies have demonstrated the involvement of genes modulated by single modulator genes in cancers, including breast cancer.
Interestingly, groups of gene pairs that were modulated by single modulators (ranked from 2nd to 11th) were found with higher frequencies than those modulated by multiple modulators.
For this reason, we evaluated whether its levels would be modulated by single and combined treatments.
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Through functional annotation analysis, we showed that genes modulated by merely single modulator or co-modulated by multiple modulators play important roles in breast cancer.
Our simulations predict enhanced thermoelectric efficiency in Si nanowires modulated by a single constriction compared to the corresponding non-modulated nanowires.
Ignoring preferential attachment in Eq. 2 leads to the lognormal model, containing a lognormal temporal decay modulated by a single fitness parameter.
In each optical network unit (ONU), the obtained optical carrier is modulated by a single MZM to provide the VPN and upstream communications.
In the proposed scheme, the signal for downstream was modulated by a single CW laser diode and remodulated in the optical network unit as an upstream, the proposed WDM PON scheme can offer the SCM signal for broadcasting service.
In summary, RS neurons often show responses to more than one call type, whereas we do see examples of them being strongly modulated by a single call type.
We assessed in 1,408 postmenopausal breast cancer patients from the German MARIE study whether cancer specific survival after adjuvant chemotherapy, anthracycline chemotherapy, and radiotherapy is modulated by 127 Single Nucleotide Polymorphisms (SNPs) in 21 BER genes.
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