Sentence examples for modulate the shape from inspiring English sources

Furthermore, our structural results defining the open p38α C-lobe pocket provide a detailed framework for the design of novel small molecules with affinities comparable to active-site binders: to bind and potentially modulate the shape and activity of p38α in predetermined ways.

However, other membrane-associated proteins also can modulate the shape of the membrane, usually by forming polymeric scaffolds [12], [27].

Phe330 can adopt different conformations in the presence of different ligands thus providing an efficient way to modulate the shape and size of the choline binding pocket, even acting as a molecular lid.

We propose that this is due to interference in automatic inverse modeling of the positions and movements of articulators that modulate the shape of the vocal tract.

Although these slower motions do not modulate the shape of an EPR spectrum, conformational exchange typically places the label in two or more environments where the label executes different motions on the nanosecond time scale.

Here, we confirm for the first time that these muscles can modulate the shape of the melon, and that the beam width is indeed very adaptable in these animals.

Therefore, PTMs that introduce charged entities, such as phosphate groups or neutralize existing charges, such as lysine acetylation, are likely to modulate the shapes of disordered protein ensembles.

In particular, the ionization state of the E71-D80 proton-sharing pair modulates the shape of the potential profile in the vicinity of the selectivity filter.

The study also highlighted the role of large scale atmospheric processes in modulating the shape of the AOD time series over the regions with significant abundance of natural aerosol component (dust).

Compared with conventional Cu/SiO2-stacked ReRAM fabrication methods, Cu CDT easily modulates the shape of the Cu/SiO2 interface and the thickness of the SiO2 switching layer during Cu deposition.

Voltage-dependent potassium ion (K+) channels (Kv channels) conduct K+ ions across the cell membrane in response to changes in the membrane voltage, thereby regulating neuronal excitability by modulating the shape and frequency of action potentials.