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The novel gyroid lattice structure was employed to modulate the drug release from all four polymers.
Such constructions allow to modulate the drug release conditions according to the target tissue and the activity of its enzyme and tumor marker.
The core tablets were coated with blends of ethyl cellulose (EC) and hydroxypropyl methyl cellulose (HPMC) to modulate the drug release.
POSS aggregated to form crystals serving as physical crosslinks on the nanometer scale, while the soft segments were designed carefully to modulate the drug release rate from the POSS TPU stent coatings in PBS buffer solution, with 90% of the drug releasing from within half a day to about 90 days.
NLCs enhance the apparent solubility and dissolution of PWS drugs in the gastrointestinal tract, and/or modulate the drug permeability and fate across the intestinal barrier, opening new perspectives in the field of innovative medicines for oral administration of PWS molecules.
Therefore, it is desirable to evaluate nsSNVs of interest in their ability to modulate the drug response.
Similar(51)
The aim of this study was to investigate pharmaceutical potentialities of a polymeric microparticulate drug delivery system for modulating the drug profile of poorly water-soluble quercetin.
In vitro release studies have demonstrated two release patterns of these IPN beads for water-soluble drugs just by modulating the drug concentration, suggesting their possible applications in different delivery systems.
Furthermore, it was showed that curcumin modulated the drug efflux of yeast ABC transporters without affecting the levels of transcription genes encoding these transporters.
Alternatively, AP2-mu may contribute to a broad parasite heterogeneity that modulates the drug response to several antimalarial drugs, as seen for pfmdr1 and other members of the ABC transporter family in P. falciparum (25).
The cells that survive compound A treatment carry the genomic change induced by compound A. This genomic residual effect further modulates the drug effect of compound B, which is the key hypothesis of this study.
Related(20)
modify the drug
adapt the drug
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regulate the drug
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tailor the drug
modulate the risk
modulate the wavelength
modulate the volume
modulate the effectiveness
modulate the bone
modulate the speed
modulate the degree
modulate the cation
modulate the light
modulate the effect
modulate the invasion-metastasis
modulate the histone
modulate the host
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