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These data demonstrate that focused auditory attention in humans can selectively modulate sensory processing in auditory cortex beginning as early as 20 msec poststimulus, thereby providing strong evidence for an "early selection" mechanism of auditory attention that can regulate auditory input at or before the initial stages of cortical analysis.
The efference copy is, however, not used to generate the ongoing motor activity, but can be used to predict the outcome of the motor command [24] [28] (information of efference copies interact at several levels of the central nervous system, and often modulate sensory processing; for reviews, see [34], [35]).
Due to its projections to the visual stream, it is further likely to modulate sensory processing [ 8].
Woldorff et al. (1993) have shown that focused auditory attention can modulate sensory processing as early as 20 ms.
Cholinergic inputs to the auditory cortex can modulate sensory processing and regulate stimulus-specific plasticity according to the behavioural state of the subject.
Phillips et al. (2003) studied responses to oesophageal distention coupled with the viewing of neutral or fearful facial expressions, designed to provide an emotional context that would modulate sensory processing.
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In this experiment we found that, besides P1 response (80-120 ms) over the lateral-occipital areas, attention to both spatial and non-spatial features was able to modulate early sensory processing, as indexed by ERPs, at a latency and with a topography consistent with the earliest visual C1 response (60-100 ms) over mesial-occipital areas.
TRPV1 receptors play an important role in modulating trigeminal sensory processing and for this have been proposed as potential targets for migraine treatment.
In doing so, ketamine modulates central sensory processing of pain.
Glycinergic synapses predominate in brainstem and spinal cord where they modulate motor and sensory processing.
These results indicate that the rostral prefrontal cortex, which supports episodic cognitive control, possibly by sending a weighting signal toward the inferior parietal and middle/inferior temporal cortices that modulate saliency and sensory processing, underlies individual differences in WMC.
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