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More recently NICU's strive to include developmentally oriented care and modulate sensory input for preterm infants.
Dopamine is one of the "off switches" that helps modulate sensory input.
These neurones constitute either spinal inter-neurones that aim to modulate sensory input, or ascending processes that transmit nociceptive information to the brain via the spinothalamic, spinomesencephalic, spinoreticular and spinocervical tracts.
The descending pain pathways descend from the brainstem, hypothalamus and cortical structures, and modulate sensory input from primary afferent fibers and projection neurons in the dorsal horn of the spinal cord [ 6].
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It is thus possible that ASTs, MIPs and DTKs modulate sensory inputs onto central neurons.
Neurogenesis-induced rewiring occurs in a manner that permits the functional integration of new neurons while maintaining a balance of activity by recruiting inhibitory interneuron networks in the case of the DG, or by directly modulating sensory input and principal neuron output in the case of the OB.
Since different alpha frequencies were recorded depending on the sensory modality (visual vs. auditory stimuli) it was further suggested that the hippocampus serves a gating mechanism for alpha signals [15], [16], modulating sensory input.
Calcium imaging has also shown that sniffing modulates sensory input.
However, little is known about whether eCBs are important signalling mediators in modulating direct sensory input from the entorhinal cortex through the PP pathway in the hippocampal CA1 region.
Neuronal activity in this region is modulated by sensory input from taste receptors and lingual somatosensory receptors[ 30].
In the somatosensory cortex, bursting develops in vitro, emphasizing its intrinsic nature, but is strongly modulated by sensory inputs [ 22] and interhemispheric connections in vivo [ 30].
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