Sentence examples for modulate nociceptive processing from inspiring English sources
The brainstem contains descending circuitry that can modulate nociceptive processing (neural signals associated with pain) in the dorsal horn of the spinal cord and the medullary dorsal horn.
When applied intrathecally, S1P and FTY720 improve pain-related behavior in the formalin assay and modulate nociceptive processing via inhibition of neuronal cAMP synthesis at spinal cord level [32], [53].
It seems logical to assume, but remains unproven, that these external factors modulate nociceptive processing at a supraspinal or cortical level [ 7].
However, there was no significant difference in paw withdrawal latencies between the LC/SC-lesioned rats and sham-operated rats, indicating that unilateral activation of the LC/SC is sufficient for modulating nociceptive processing in the dorsal horn.
Previously, we have demonstrated a novel functional role of spinal CB2 receptors in modulating nociceptive processing in neuropathic, but not sham-operated, rats (Sagar et al., 2005), supporting their presence in the spinal cord of neuropathic rats (Zhang et al., 2003; Wotherspoon et al., 2005; Beltramo et al., 2006).
After icv administration of opioids, the MORs in the ventral region of PAG [40] play an important role in the supraspinal pathways that modulate spinal nociceptive processing [41].
After icv administration of opioids, the MORs in the ventral region of PAG play an important role in the supraspinal pathways that modulate spinal nociceptive processing (66, 67).
Experimental data suggest that the posterior hypothalamus is involved in the modulation of nociceptive processing in humans [29].
Transcranial direct current stimulation (tDCS) of the primary motor cortex has been shown to modulate pain and trigeminal nociceptive processing.
It is suggested that several attentional processes can modify nociceptive processing in the brain at different stages.
The animal experimental results showed that both peripheral and central changes in nociceptive processing are involved in this process [ 6].
