Sentence examples for modulate membrane trafficking from inspiring English sources

The β subunits, which bind to α subunit covalently or non-covalently, modulate membrane trafficking, voltage dependence, and channel gating kinetics (Catterall, 2012b, 2014).

Arf6 was found to interact with the Vo c subunit and it was proposed that through this interaction, the vATPase could modulate membrane trafficking in the endosomal system [47].

By controlling the ubiquitination status of cargo molecules, transport machinery proteins, or the structural components of an organelle, these enzymes can modulate membrane trafficking via a variety of mechanisms such as affecting the sorting of a specific cargo, impacting the level or activity of a trafficking regulator, or modulating the assembly/disassembly of a vesicular compartment.

In this way ARL1 could act as a sensor and modulate membrane trafficking at the onset of COS 5.44 induced membrane permeabilization.

Depletion of Rab35, another GTPase proposed to modulate membrane trafficking in cytokinesis was without effect on any Exocyst polypeptide levels (data not shown).

Using primary rat alveolar macrophages, we could show that SP-A specifically and transiently modulates endocytic/phagocytic membrane trafficking via regulation of Rab GTPases thereby functionally enhancing the lysosomal delivery of GFP-labeled Escherichia coli in these cells.

Our observation that TNF-α promotes the entry of several pseudoviruses to polarized hepatoma cells suggests that TNF-α affects the function or distribution of several different classes of viral receptors, most likely through modulating membrane receptor trafficking.

In 2006 Ferguson et al. were the first demonstrating that pulmonary C-type lectins can modulate Rab-regulated intracellular membrane trafficking.

Tollip modulates TLR signaling and membrane trafficking processes through its interaction with both proteins and phosphoinositides.

Here, we have summarized how Chlamydia modulates cellular signaling and membrane trafficking.

We have shown that mechanistic target of rapamycin (mTOR) signalling regulates system A amino acid transport by modulating the ubiquitination and plasma membrane trafficking of sodium-coupled neutral amino acid transporter 2 (SNAT-2) in cultured primary human trophoblast cells.