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They often serve as precursors for modification with various tailoring enzymes that result diverse compounds with numerous bioactivities such as thaxtomin A and gliotoxin.
Here, we report a further improvement of protein contrast agents ProCA1 for in vivo imaging by protein modification with various sizes of polyethylene glycol (PEG) chain.
It has been reported that the dispersity of GoldMag can improved through surface modification with various macromolecular organic compounds, such as 11-mercaptoundecanoic acid (MUA) [7], polystyrenesulfonate (PSS) [8], and polyethylenimine (PEI) [9].
The surface sol gel technique was used to deposit ultrathin metal oxide gel film to uniformly coat the cellulose nanofibers of bulk cellulose substances and for further modification with various functional building blocks to fabricate nanostructured materials.
The distinct hierarchical structures and morphologies of natural cellulosic substances (e.g. ordinary laboratory filter paper) provides ideal platforms for the surface modification with various guest species that are immobilized or deposited onto the surfaces of the exquisite structure details.
By modification with various biocompatible molecules, significantly improved stability and reduced toxicity have been achieved.
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Methods: Various TAFC modifications with various substitution (different carbon chain length acyl compounds as well as charge substitutents) were prepared and labelled with 68Ga.
Thereafter, these polymer chains are maturated by sulfated modifications with various sulfotransferases, which transfer the sulfate group from a sulfate donor, 3′-phosphoadenosine 5′-phosphosulfate, to the corresponding hydroxyl groups at each sugar residue of the backbone, and by epimerization of the GlcUA residue with C5-epimerases [ 3– 5, 8, 9, 35].
Biological processes, leading to reduced radiation sensitivity in presence of genetic disorders and/or immune deficiencies, are not likely to have been involved in such an effect modification observed with various PFs.
It has been known for 40 years that aging is linked to the change of DNA cytosine methylation (5-methylcytosine [5-mC]) [ 2], which is one of the best-characterized epigenetic modifications associated with various physiological and pathological processes [ 3, 4].
Recently, Ernst et al. [ 20] applied a multivariate hidden Markov model (HMM) to ChIP-Seq data of 9 histone modifications to infer chromatin modification states associated with various types of functional DNA elements, including enhancers.
Related(20)
adjustment with various
modification with other
modification with several
modification with multiple
change with various
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alterations with various
changes with various
modifications with various
modification with available
modification with little
modification with inorganic
modification with hydrophilic
modification with high
modification with stearic
modification with p-Bromophenacyl
modification with silver
modification with N-terminal
modification with oxalic
modification with carbonaceous
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