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Furthermore, high caffeine consumption has been found to be a modest risk factor for onset of chronic daily headache [8].
Some research has identified dietary and medicinal caffeine consumption, specifically OTC caffeine combinations, as a modest risk factor for progression from episodic to chronic headache [91, 92].
In addition, there was a trend of increasing number of DD genotype in older PD patients and the modest risk factor of DD genotype in PD was due to the significant difference of the DD homozygosity in old patients with onset age at or after 60 years.
Other association studies have suggested that the p.I22M polymorphism is modest risk factor for Down syndrome [11] and NTD [9].
Sedentary work may be a modest risk factor.
Epidemiological studies suggest that dyslipidemia is a modest risk factor for PAD (Selvin and Erlinger 2004; Norgren et al 2007).
Similar(51)
Of the several modest risk factors that have been identified for pancreatic cancer, including obesity, diabetes, physical inactivity, chronic pancreatitis and dietary factors [ 7- 12], cigarette smoking has been reported most consistently [ 2, 13- 17].
Although recent studies have shown that heredity is a dominant factor in lumbar disc degeneration, heavy lifting and awkward working positions as well as obesity and joint injury may be modest risk factors for disc degeneration, and also for arthrosis of the knee and hip [ 18, 19].
A stepwise logistic regression analysis of the presence of the DD genotype and data on risk factors for PD confirmed that the homozygote DD genotype was a modest independent risk factor for PD (OR=1.32, 95% CI=1.12 2.16).
There is evidence that modest changes in risk factor levels can bring about large improvements in health and thus reduce this burden of care [ 1].
Our null finding must be tempered by considerations of statistical power – we could have missed modest differences in risk factor profiles.
Related(16)
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