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Exact(4)
Most physicians would be comfortable categorizing a moderately large effect as clinically important [ 28].
Evidence for the limitation of sample size of many studies is given by the many reports in which genotype was inferred to have no effect when the associated P values fell in the range 0.05 0.10, even though moderately large effect sizes were observed.
Although our study provides some evidence for a small effect of STI co-infection on viral loads, we cannot rule out the possibility of no effect, or the possibility of a moderately large effect (the upper credible interval is 0.83 log10.83
Despite the difficulties in obtaining unbiased estimates of effect size, it appears that, in contrast to traits such as stature (where effect sizes of 0.1% of the variance are the norm) (31), at least some of the genetic basis of the optic disc measures studied lies in the range of moderately large effect sizes.
Similar(56)
However, given that MLDA has well-documented and moderately large effects on alcohol consumption among young people, and the sharp discontinuity that is observed at age 21, it is unlikely that other role transitions drive these results.
The majority of SNPs (80.3%) affecting sleep were at low frequency and had moderately large effects.
"Easy" classification problems contain individual genes with large effects or multiple independent genes with moderately large effects.
Patients in all weight change categories showed deterioration in MCS scores, ranging from small to moderately large effects.
Thus, modest GWAS evidence could implicate moderately-common loci and/or moderately-large effect sizes at the actual risk locus.
The model incorporates moderately large displacement effects as well as material nonlinearity to assess the performance of steel beams exposed to thermal loading in a compartment fire, and it considers the yielding and development of catenary action affects with an increase in the temperature.
Nonetheless it still only screened <15% of the human genome, and was only powered to identify moderately large genetic effects compared with the magnitude of genetic associations that are typically found in common diseases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com