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Although these point estimates are consistent with effectiveness, the CIs are wide which could be consistent with a small effect or quite large effect.
However, we would argue that the two-fold effect is already a quite large effect given the importance of TORC1 activity for cell growth, and is enough to establish a function of the Kog1-bodies – something that has yet to be done for other bodies/granules as we mention in the Discussion.
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Taken individually, most of the parameter substitutions have little effect on the overall model performance, although a handful have quite large effects, and are investigated more thoroughly.
Quite large effects with regard to the radial dependence of breakthrough curves were found for a laboratory adsorber of p = 21.
Even quite large effects of medication (up to 8 percentage points absolute risk reduction) had a smaller impact on acceptance to medication than personal experience with cardiovascular disease.
Numerical results indicate that horizontal multi-support excitations have a quite large amplification effect on the seismic responses of the trussed arch.
HENDRIK HERTZBERG: It would have quite a large effect.
This provides some evidence that the massage can have quite a large effect in just over a third of patients.
Methylation of PITX2 was very strongly associated with prostate cancer death (p < 0.0001) and had quite a large effect size (odds ratio 2.7), which was independent of Gleason score, prostate specific antigen or stage.
Further, the sample sizes required to map rare variants are much higher than for common variants, unless those rare variants have quite large individual effects.
The main finding is quite compelling: large effects of PFC inactivation on decision-making, little or no effect of PPC inactivation.
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