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Soluble Aβ species are mobile in solution and extracellular soluble Aβ may exit slices by diffusion.
Similarly, carbohydrates have traditionally been viewed as more flexible and mobile in solution when compared to globular proteins.
A similar dynamics run on the complex with 15 suggested that it too may be mobile in solution, with carboxylate access even to the Arg204 side chain.
Relaxation enhancements in a paramagnetic environment reveal that both the octanoyl group on Ser3 and the aromatic group on Phe4 are inserted deep into the hydrophobic core of phosphocholine assemblies while the remaining peptide is freely mobile in solution.
However, recent NMR analysis on SENP1 has revealed that Trp-465, the aromatic residue constituting the 'lid' is highly mobile in solution, thus allowing substrates to access the active site [ 42].
In the bead-based multiplex arrays, the reactions take place among capture entities and analytes which are freely mobile in solution, providing more sensitivity to measure circulating levels of analytes.
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Solution NMR studies show that the region corresponding to the βN/β4 hairpin observed in the crystal is highly mobile, and in solution, the shorter β4-strand is followed by a break in the strand and a β3′-β3″ hairpin.
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Organic N compounds are less mobile in soil solution [25] and hence may mainly be acquired through diffusion.
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