Sentence examples for mitochondrial translation system from inspiring English sources

Both of the two kinds of CAU-tRNAMet can recognize AUA codon in the fruit fly mitochondrial translation system.

The mitochondrial translation system is thus organized in a very specific way.

Unravelling the vagaries and intricacies of the mammalian mitochondrial translation system will keep the field busy for some time to come.

Since the metazoan mitochondrial translation system comprises a reduced tRNA gene set of usually 22 tRNA genes, each tRNA gene has to recognize different codons (usually two or four codons), which often differ only in the 3rd codon site.

It is of particular relevance to those disorders where the primary defect is in the mitochondrial translation system, which applies to many of the commonest pathological mtDNA mutations such as the 3243G > A MELAS mutation, as well as an increasingly recognized subset of nuclear gene mitochondrial disorders exhibiting multiple OXPHOS deficiencies (Pearce et al. 2013).

The mRNA for the G elongation factor mitochondrial 1 protein (GFM1), one of three factors required by the elongation stage of the mitochondrial translation system, significantly increased in expression in PBMC from the N'Dama cattle over time and was consistently higher in N'Dama compared to Boran at all time points.

However, whether the mitochondrial translation systems of these seven marine bivalves acquire distinct elongator and initiator tRNAMet genes needs further investigations.

Furthermore, despite impressive efforts to reconstitute in vitro mitochondrial translation systems (Yasukawa et al, 2001; Takemoto et al, 2009), results have been limited.

Almost all of the initial attempts to establish in vitro mitochondrial translation systems started with a heterologous system often combining yeast or occasionally mouse mt-mRNAs, or simply homoribopolymers together with a mix of yeast and eubacterial components [126 128].

And importantly, this implies that the explanation(s) for the porous nature of the mammalian mitoribosome must be sought in the process -es) underlying the deletion bias of metazoan mitochondrial genomes, and not in unique functional process -esof mitochondrial translation systems.

Mutations in SARS2 resulting in decreased aminoacylation of one tRNA isoacceptor (tRNASerAGY or tRNASerUCN) by the serine amino acid are expected to adversely affect mitochondrial translation systems and lead to derangements in the synthesis of mitochondrial proteins and consequently in energy supply.