Sentence examples for mitochondrial fusion system from inspiring English sources

This is similar to other cell free fusion assay systems, including the yeast mitochondrial fusion system [ 5, 21, 22].

To verify that the rescue of the defective Ca2+ uptake in Afg3l2 −/−::OPA1v1 and Afg3l2 −/−::OPA1v1Q297V was specifically caused by the recovery of mitochondrial morphology and not by a different effect of OPA1 overexpression in the inner membrane, we tested whether it can be achieved by stimulating mitochondrial fusion through a different molecular system.

The integration of scientists from these fields into the study of mitochondrial dynamics will depend upon the availability of robust assay systems to quantify mitochondrial fusion.

However, what is relatively clear is that loss of PINK1 does not result in increased mitochondrial fusion [36], at least in this model system.

Mitochondria typically form a reticular network that is a dynamic interconnected system that undergoes constant cycles of mitochondrial fusion and fission [ 12– 12].

In the mammalian system there are three large GTPases that control mitochondrial fusion.

Using our cell-free assay system, we have provided direct evidence that shows how mitochondrial fusion is tightly regulated by cytosolic signaling cascades.

This assay system has allowed us to establish the energetic requirements for mitochondrial fusion.

These technical issues make limited progress in the field of mitochondrial fusion, thus making it virtually impossible to identify and dissect the unique stages of the reaction, experiments which are routinely performed in other membrane fusion systems [ 12].

Mitochondrial fusion is essential for maintenance of mitochondrial function.

Westermann, B. Bioenergetic role of mitochondrial fusion and fission.