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Exact(6)
What is known is that the transcriptional blockade of p53 by α-amanitin induces p53 mitochondrial localisation and Bax accumulation, and activation in mitochondria.
We therefore employed rhodamine 123 to monitor possible changes in mitochondrial localisation and clustering in normal and transformed fibroblasts following the MR-4 treatment.
Computer analysis of the putative transit peptide (Emanuelsson et al. 2000) produced high scores (0.8 0.9) for mitochondrial localisation and no indication for targeting to chloroplasts.
In the species A. terreus, Colletotrichum graminicola, Dothistroma septosporum and Mycosphaerella fijiensis, two to three CBR sequences with TargetP-predicted mitochondrial localisation and higher similarity to SsMCR1 were retrieved using SsCBR1 as a query sequence.
The protein contains a BH3 domain that induces apoptosis (Yasuda et al, 1998) and a C-terminal transmembrane domain that is required for both its mitochondrial localisation and its proapoptotic activity (Chen et al, 1997, 1999; Yasuda et al, 1998); it has been suggested that BNIP3 mediates a necrosis-like cell death by causing mitochondrial dysfunction (Harris, 2002).
Most of the cells grown under these conditions showed changes in their cell profiles, as well as disorganisation of microtubules and microfilaments, and an increase in the number of apoptotic cells in the culture [ 91– 96], in addition to alterations in mitochondrial localisation and clustering behaviour [ 56].
Similar(54)
Such processing of L. major MCA influences its subcellular location, as the enzyme encodes a mitochondrial localisation domain and a cytosolic retention domain that together modulate the balance of MCAs between the mitochondrial and cytosolic compartments.
The mitochondrial localisation of ScMMT1 and ScMMT2 [ 47] corresponds to the plasma membrane location of the prokaryotic members [ 7, 12].
We demonstrate vasculature specific expression of the Arabidopsis ProDH2 gene (At5g38710) as well as enzymatic activity and mitochondrial localisation of the encoded protein.
Mitochondrial localisation of ProDH1-GFP and ProDH2-GFP fusion proteins in Arabidopsis demonstrated functionality of the ProDH-mTPs in the native organism.
Immunohistochemistry revealed that PLIN5 was present on LDs and showed punctuate mitochondrial localisation.
Related(14)
mitochondrial tracking and
mitochondrial location and
mitochondrial positioning and
mitochondrial function and
mitochondrial fusion and
mitochondrial localization and
mitochondrial activity and
mitochondrial disease and
mitochondrial genome and
mitochondrial depolarization and
mitochondrial morphology and
mitochondrial health and
mitochondrial quality and
mitochondrial fragmentation and
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