Sentence examples for mitochondrial quality and from inspiring English sources

Despite the central role of mitochondria in metabolism, the relationship between mitochondrial quality and insulin action remains unclear.

Clarification of the role of mitochondria in regulating key cellular processes including metabolic flux, autophagy, and apoptosis will drive the development of novel therapeutic strategies for maintaining mitochondrial quality and improving human health.

Macromitophagy controls mitochondrial quality and quantity.

Consequently, cells need to be able to monitor mitochondrial quality and quantity.

Fission is important for maintaining mitochondrial quality and integrity since it is involved in the selection of dysfunctional mitochondria.

This review explores the synergistic mechanisms that control mitochondrial quality and function and ensure cellular bioenergetic homeostasis.

In trying to understand the reasons for these differences, it is worth noting that the seemingly straightforward functional subclassification of PINK1 and Parkin mutations as principally affecting mitochondrial quality control, and Mfn2 and Opa1 mutations as primarily impacting mitochondrial dynamism, may be misleading.

Understanding mitochondrial quality control and the interactions between the organelle and the nucleus will be crucial in developing therapies for the plethora of diseases in which the pathophysiology is determined by mitochondrial dysfunction.

Although the causative genes for autosomal recessive PD, Parkin, PINK1 and DJ-1, share a common pathway, at least in part, in mitochondrial quality control and protein quality control, their precise relationship remains elusive.

Other studies again outline the key role of HMGB1 in mitochondrial quality control and autophagy [ 124– 124].

Compromised mitochondrial quality control and Ca2+ handling are instead suggested to be primary events.