Sentence examples for mitochondrial bioenergetic function from inspiring English sources

There is a clear need for a better understanding of the interaction of HBO and mitochondrial bioenergetic function in the face of CO poisoning.

The current study was designed to examine the regulatory role of mitochondrial bioenergetic function in controlling the initiation and execution of the apoptotic process of OHCs.

Our combined results focus attention on lipid metabolism as a critical HSP pathway with a deleterious impact on mitochondrial bioenergetic function.

Proper regulation of mitochondrial size and shape through fission and fusion assures optimal mitochondrial bioenergetic function while enabling adequate mitochondrial transport to accommodate local energy demands unique to neuronal architecture.

Thus, transcriptional down-regulation of several components of the TCA cycle and ETC by 14 D of immobilization is closely mirrored at the level of enzymatic function and is consistent with a general attenuation of mitochondrial bioenergetic function.

Our observation that PINK1 deficiency in mouse brain leads to a combined impairment of activity of respiratory complex I+III+IV and II+III+IV, mitochondrial membrane potential Δψm and ATP generation at old age are consistent with a defect in mitochondrial bioenergetic function.

Inhibition of mitochondrial dynamics caused by Aβ peptides or fibrils did not instantly affect mitochondrial bioenergetic and function.

Preserving mitochondrial mass, bioenergetic functions and ROS (reactive oxygen species) homoeostasis is key to neuronal differentiation and survival, as mitochondria produce most of the energy in the form of ATP to execute and maintain these cellular processes.

Thus, MRPs play a critical role in mitochondrial protein synthesis and bioenergetic function [ 18, 19].

To assess how loss of mitochondrial fission affects intrinsic bioenergetic function in neurons, we co-transfected Drp1lox/lox hippocampal neurons with Cre recombinase (to delete Drp1) or a vector control, the ATP-based FRET sensor (ATP1.03YEMK), and mitoFarRed (to visualize mitochondria).

Abnormalities in mitochondrial membrane potential (MtMP) are associated with mitochondrial dysfunction through alteration in bioenergetic function (42, 43).