Sentence examples for mitochondrial antioxidant function from inspiring English sources

NRF2 can regulate mitochondrial antioxidant function [55].

Taken together, these results demonstrate that the expression of miR-17* in PC-3 cell reduces the tumorigenicity, at least in part, by inhibiting mitochondrial antioxidant function.

It is noteworthy that both 4-HNE and 3-NT formations were reduced not only in the OC but also in the stria vascularis by MB pretreatment, indicating that MB could augment the mitochondrial antioxidant function in the stria vascularis, which is highly metabolically active and is most commonly affected by mitochondrial dysfunction.

Failure to control the oxidation state of proteins can arise from mitochondrial disease and compromised antioxidant function.

We found that PGC-1 α capacity to shift the balance toward mitochondrial biogenesis relies upon its antioxidant function.

Therefore, the antioxidant function of mitochondrial HK II, which was also observed by others [136], could have a key survival role by maintaining the PTP locked.

This protection occurs in a DMPK-sensitive fashion, as the inhibition of Src enzymatic activity selectively affects the viability of DMPK-expressing cells, in accord with a general survival and antioxidant function of mitochondrial Src.

Thus, the antioxidant function of the mitochondrial HK II could have a key survival role by maintaining the PTP locked, as recently proposed for cardiomyocytes.

The results demonstrate that suppression of mitochondrial antioxidant enzymes is a mechanism for the tumor suppressor function of miR-17*.

The antioxidant function of HK II relies on its mitochondrial binding as such, and is independent of its enzymatic activity.

Consequently, on H2O2 burst, iPLA2γ (or another isoform, if activated, but apparently not iPLA2β) ensures an antioxidant function in concert with UCP2, which then attenuates mitochondrial superoxide formation by mild uncoupling (4, 18, 36) (Fig. 3).