Sentence examples for mitochondrial bioenergetic efficiency from inspiring English sources

We conclude that CR increases lipid peroxidation, inflammation and apoptosis, while decreasing mitochondrial bioenergetic efficiency, protein oxidation and stress response in G93A mice.

We propose that CR increases the protein content of subunits of mitochondrial repiratory chain in male G93A mice to compensate for reduced mitochondrial bioenergetic efficiency.

The findings of this study highlight the complexity of coordinated regulation of mitochondrial bioenergetic efficiency and cellular redox homeostasis in skeletal muscle, and functional capacity of older adults.

The life-extending properties of CR have been observed in insects, rodents and non-human primates, and are mainly attributed to a reduction in mitochondrial oxidant production and an increase in mitochondrial bioenergetic efficiency [3] [7].

However, this increase did not translate into enhanced mitochondrial oxidative capacity since the ratio of COX to citrate synthase activity (marker of mitochondrial bioenergetic efficiency) is reduced in CR male G93A mice.

By favoring either connected or fragmented architectures, mitochondrial dynamics regulates bioenergetic efficiency and energy expenditure.

CR induces mitochondrial biogenesis and bioenergetic efficiency in both animals and humans [26] [28].

Here, we show that 10 weeks of EPA supplementation partially restores mitochondrial oxidative capacity and bioenergetic efficiency in aging skeletal muscle, but DHA does not.

Amo et al. [ 27] reported that mitochondrial bioenergetic capacities and coupling efficiencies in cultured carcinoma cells did not differ between transmitochondrial cybrids harbouring mitochondria with haplogroup H and those harbouring mitochondria with haplogroup T [ 27].

These fatty acid changes alter mitochondrial membrane fluidity, which lowers bioenergetic efficiency (Ellis et al., 2005).

The mitochondrial lipidome influences ETC (electron transport chain) and cellular bioenergetic efficiency.