Sentence examples for mitochondrial activation and from inspiring English sources

In contrast, in the RIPA branch, IRF3 is activated by LUBAC-mediated linear ubiquitination, which triggers its interaction with BAX to cause mitochondrial activation and apoptotic cell death.

Based on these data, the phenotype of reduced lipid droplet size, increased lipolysis and reduced TAG storage appears to be the primary defects in the WAT of Fsp27−/− mice, while increased mitochondrial activation and up-regulation of BAT specific markers are secondary effects.

Compared with glucose metabolism, cellobiose metabolism induced mitochondrial activation and reduced amino acid biosynthesis under fermentation conditions.

These data indicate that resetting human PSC is accompanied by a profound mitochondrial activation and metabolic realignment.

The gene PPARGC1B, an important transcription factor and regulator of mitochondrial activation and OxPhos (Handschin and Spiegelman 2006), was also annotated with these terms.

Differences in gene expression between cellobiose and glucose metabolism revealed by RNA deep sequencing indicated that cellobiose metabolism induces mitochondrial activation and reduces amino acid biosynthesis under fermentation conditions.

T cell receptors activated the T cell proteome and phosphoproteome with discrete kinetics, marked by early dynamics of phosphorylation and delayed ribosome biogenesis and mitochondrial activation.

IMAC or PtP may be involved in pathological propagation of ROS production and mitochondrial activation in skeletal muscle.

99mTc-labelled hexakis-2-methoxyisobutylisonitrile is a radiopharmaceutical which accumulates in tissues with high cellular density and mitochondrial activation as it can be found in malignant tissues.

Also, depletion of p66Shc in cells has no metabolic consequences, whereas p52/46 depletion in cells causes increased insulin sensitivity and mitochondrial activation.

The authors are currently investigating the effects of nSP70, nSP70-C, and nSP70-N on cytotoxicity, protein adsorption, cellular uptake, ROS generation, lysosomal stability, mitochondrial activity, activation of caspase 3 and 7, and mode of cell death (apoptosis versus necrosis).