"We have to figure out the minimum doses and modes of delivery, example possible side effects and optimize timing before it could be considered as a possibility for human trials," Dr. Reeves told The Huffington Post in an email, adding that funding for such research was in short supply.
The HI was defined using the following equation [ 11]: (2) HI = D 2 % − D 98%% D 50%%, where D2% meant near-maximum dose, D98% meant near-minimum dose, and D50% meant the dose that half volume of the PTV received.
Supplementary Table 1 describes the minimum dose used and the percentage of "unclassifiable" diabetic patients for each antidiabetic drug (<5% of all patients).
This study is part of a series to determine the minimum dose (g/day) and frequency (number of administrations/day) required for xylitol chewing gum to be effective in reducing mutans streptococci levels in plaque and saliva.
For the PTVtrim, the following constraints were used: uniform dose (42.56 Gy), maximum dose (45.5 Gy, point dose), and minimum dose (40.6 Gy).
The minimum dose was γ, and this dose was used during the intensive care unit (ICU) stay.
