Sentence examples for required dose and from inspiring English sources
A considerable number of patients required dose and schedule modifications.
Increasing bioavailability provides the twin benefits of reducing the required dose and thus the cost of the drugs and reducing the individual probabilities of underdosing or overdosing.
Encapsulated drugs are advantageous due to such properties as high stability, better bioavailability, controlled drug release, a long blood circulation time, selective organ or tissue distribution, a lower total required dose, and minimal toxic side effects.
The design of appropriate innovative formulations for PWS drugs will allow for adequate bioavailability, reduction of the required dose and oral delivery of drugs that would otherwise need the parenteral route.
The goal is to search for a synergistic effect and thereby reduce the required dose and inhibit the development of resistance.
The total daily intake of fluoride from food is about 0.2 0.5 mg which is about only 10 15 % of the required dose and hence we have to be dependent on groundwater to fulfil this deficit (Boyle and Chagnon 1995).
Millions of Americans are skipping required doses and putting their health at risk because they can't afford to renew their prescriptions.
This treatment strategy simultaneously decreases NAD+ synthesis while increasing NAD+ consumption, reducing required doses and treatment times for both drugs and increasing potency.
In that sense, DCA could both precede and be given concurrently with chemotherapy or radiation therapy, in an attempt to increase their effectiveness, decrease the required doses and limit the toxicity of standard therapies (Cairns et al, 2007).
Although 19 (34.5%) and 20 (36.4%) patients required dose reductions and delays, respectively, the mean relative dose intensity was 93.4% (range, 63.6 100.0%).
Eleven patients required dose modification and nine discontinued due to AE. CONCLUSION: Oral vorinostat was effective in treatment refractory MF/SS with an acceptable safety profile.
