minimal binding to

USAGE SUMMARY

The phrase "minimal binding to" is correct and usable in written English.
It can be used in contexts discussing interactions, relationships, or connections, particularly in scientific or technical writing. Example: "The study found that the compound exhibited minimal binding to the target receptor, suggesting low affinity."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

34 human-written examples

Genetic evidence indicates that these mutations share a common gain of function, but it is unclear whether the shared function is dominant negative activity, neomorphic production of (R -2-hydroxyglutarate (2HG), oR -2-hydroxyglutarateR -2-hydroxyglutaratee cancer-derived IDH1 R132HGutants bind IDH1-WT but that three cancer-derived IDH2 R172 mutants exert minimal binding torIDH2-WT.

Duke University

We show by coprecipitation that five cancer-derived IDH1 R132 mutants bind IDH1-WT but that three cancer-derived IDH2 R172 mutants exert minimal binding to IDH2-WT.

Plosone

In vitro fluorescence microscopy evaluation of cKNGRE-OG demonstrated binding and active uptake by CD13+ cancer cells and minimal binding to CD13− cancer cells.

Journal of Controlled Release

We formulated particulate nanocarriers using poly(lactic-co-glycolic acid) (PLGA) and PLGA-polyethylene glycol (PLGA-PEG) polymers to generate sub-100 nm nanoparticles with minimal binding to extracellular brain components and strong binding to the Fn14 receptor – an upregulated, conserved component in invasive GBM.

Journal of Controlled Release

Fig. 9 Distribution of [18F]DCFPyL in the blood (top) revealing only minimal binding to plasma proteins and therefore good bioavailability and evaluation of the metabolic stability of [18F]DCFPyL (bottom) following injection in BALB/c mice (n = 3).

EJNMMI Research

ZNF198 exhibited minimal binding to HDAC1 alone.

Plosone

Human-verified similar examples from authoritative sources

Similar Expressions

25 human-written examples

The binding of the ElSalv/57 natural variant (carrying the Q226L HA mutation) showed predominant binding signals to α2,6 and only minimal binding signals to α2,3 glycan receptors (Figure 4).

Plosone

Using peptide SPOT arrays, we identified the minimal binding epitope to be EKLMKAFESLKSFQ, comprising the N-terminal residues 5 18 of Htt and including the first residue of the poly-Gln stretch.

Journal of Molecular Biology

As expected, Flt1[2]-Fc only had a minimal binding activity to VEGF-A, confirming a binding requirement for the flanking sequence.

BMC Cancer

The minimal half-life, 9 min, was observed for the allele -35G which corresponds to minimal binding affinity and to a maximal dissociation rate of the complex TBP-TATA.

BMC Genomics

(D ) Representative binding assays of Mss116 MBP-D1 (0–6 μM) to a 5′ FAM-B-DNA duplex (100 nM) to demonstrate minimal binding of D1 to the B-DNA duplex under these experimental conditions.

eLife

Expert writing Tips

Best practice

When describing experimental results, use "minimal binding to" to precisely convey that an interaction was tested but yielded negligible results. This is more informative than simply stating there was no interaction.

Common error

Be careful not to use "minimal binding to" when there is truly no binding at all. "Minimal binding" implies a very small amount of interaction, while "no binding" indicates a complete absence of interaction. Use the correct term to accurately reflect your data.

Linguistic Context

The phrase "minimal binding to" functions as a descriptive term, specifying a low level of interaction between two entities. As Ludwig AI indicates, the phrase is grammatically correct. Examples show its usage in scientific contexts.

Expression frequency: Common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "minimal binding to" is a grammatically sound and common expression, predominantly used within scientific contexts to describe a weak interaction between entities. Ludwig AI validates its correctness, with examples illustrating its use in research articles and technical reports. While alternatives like "weak affinity for" and "negligible interaction with" exist, "minimal binding to" provides a specific and precise description suitable for formal, scientific communication. Remember to use this phrase accurately, ensuring it reflects a slight interaction rather than a complete absence of binding.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

weak affinity for

Focuses on the strength of attraction, implying a slight or negligible attraction.

negligible interaction with

Emphasizes the lack of significant activity or effect between entities.

limited association with

Indicates a restricted or scarce connection between items.

poor adherence to

Highlights the ineffectiveness of sticking or clinging to something.

scant attachment to

Stresses the lack of substantial linking or joining.

reduced avidity for

Refers to a diminished eagerness or enthusiasm for binding.

low propensity to bind

Indicates a reduced inclination or tendency to form a connection.

displays little binding to

Shifts the focus to the displaying entity and its action or capacity.

exhibits decreased binding with

Focuses on the showing or demonstrating, highlighting the reduction.

demonstrates little interaction with

Highlights the act of showing, while emphasizing the lack of significant activity.

FAQs

How can I use "minimal binding to" in a sentence?

You can use "minimal binding to" to describe a weak interaction between two substances, such as "The antibody showed "minimal binding to" the target antigen".

What are some alternatives to saying "minimal binding to"?

Alternatives include phrases like "weak affinity for", "negligible interaction with", or "limited association with", depending on the specific context.

Is it better to say "minimal binding to" or "no binding to"?

The choice depends on the context. "Minimal binding to" suggests a very slight interaction, while "no binding to" indicates a complete lack of interaction. Use the phrase that accurately reflects the observed results.

What does "minimal binding to" imply about the strength of an interaction?

"Minimal binding to" indicates that the interaction between two substances is very weak, suggesting low affinity or a negligible effect. It implies that while some interaction may occur, it's not significant.