Sentence examples for mild mitochondrial uncoupling from inspiring English sources

We studied the effect of mild mitochondrial uncoupling in HSCs using the two different chemical uncouplers Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP) and Valinomycin.

ROS production is very sensitive to mild uncoupling in isolated Drosophila mitochondria (Miwa et al., 2003) and mild mitochondrial uncoupling may be neuroprotective.

Our findings indicate that ROS inhibition through mitochondrial-targeted antioxidant or mild mitochondrial uncoupling is beneficial for sperm cryopreservation in yellow catfish.

Indeed, mild mitochondrial uncoupling is a highly effective intervention to prevent the formation of ROS [9], [17].

Altogether, these findings confirm that mild mitochondrial uncoupling in MCK-UCP1 mice does not cause a dystrophic or massive proteolytic degeneration in skeletal muscle.

The present study shows, for the first time, that mild mitochondrial uncoupling can inhibit HSC activation.

Mild muscle-restricted mitochondrial uncoupling had little effect on muscle overall structure, despite reduced mass and mild mitochondrial myopathy (Han and our data not shown).

It is unknown whether cardiac UCP3 levels and mitochondrial uncoupling are elevated in milder, pre-diabetic forms of obesity, and thereby form an early stage of disease progression.

In all, these findings strongly suggest that chronic muscle-restricted mitochondrial uncoupling is able to induce a mild but clear motor neuron pathology, likely as a result of the progressive degenerative process initiated at the NMJ.

This implies that mitochondrial uncoupling was already increased in septic rats (thus explaining the pyrexia) and could not be increased further by exogenous uncoupling.

This implies that increased mitochondrial uncoupling was already active in septic rats and this may explain their fever.