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Overall, we find that, similarly to CR, mild systemic uncoupling in mammals promoted by DNP leads to a stimulated response of Akt pathways, NO generation and mitochondrial biogenesis.
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Patient has mild systemic disease.
Computed tomography (CT) revealed a large anterior mediastinal mass, mild splenomegaly, bilateral pleural effusion, pericardial effusion, and mild systemic lymphadenopathy.
ASA grade is scored from 1 to 6, where 1 is a healthy person, 2 corresponds to mild systemic disease, and 3 to severe systemic disease.
This treatment was reported to be well tolerated, with only mild systemic toxicity.
These results suggest a shift towards a mild systemic pro-inflammatory state.
Infection with 9R results in a mild systemic infection.
American Society of Anesthesiology (ASA) grade estimated comorbidities: I (healthy), II (mild systemic disease), III-V (severe systemic disease).
Mild systemic symptoms like low-grade fever and chills might be present.
An increase in serum globulin levels may be reflective of a mild systemic immune response [ 63].
We studied the effect of mild mitochondrial uncoupling in HSCs using the two different chemical uncouplers Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP) and Valinomycin.
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