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Exact(6)
Of course, their individual cellular concentrations and activation states in specific cell types might prevent binding and/or detection.
An inhibitor bound at either or both of these sites might prevent binding and activation of RhoA.
This IG did not include antisense sequences of genes, but its transcription might prevent binding of a regulator of the upstream gene, which was SO0196.
Moreover, the presence of an adjacent modification might prevent binding of an antibody to the target modification, causing false negative results.
Even though the highest concentration of ebselen tested (100 μM) was diluted to below its IC50 value seen in concentration response assays, it is possible that low amounts of ebselen remaining after dilution might prevent binding.
It will be of great interest to determine how many intact TZF peptide and intact TTP protein molecules can bind to this sequence, because it might be expected that the overlapping nonamers might prevent binding to some of the neighboring nonamers by steric hindrance.
Similar(54)
Under these conditions copper binding might prevent iron binding at one or more sites.
Additionally, we also calculated geometric features of the inhibitors from 2D data like their diameter, length and width that might prevent kinase binding due to steric hindrance.
The functionality maps are also used to design a library of disubstituted indoles that might prevent the binding of the protein substrates.
GGol, at the concentrations tested might prevent the binding of squalestatin to protein geranylgeranyl transferase.
In addition, although our initial ChIP results (13) showed that very high H3K4me3 levels might prevent AIRE binding to chromatin, our AIRE ChIP-on-chip data indicate that the AIRE protein has a fairly random pattern of chromatin binding.
Related(20)
might inhibit binding
might stabilise binding
might affect binding
might promote binding
might enhance binding
might contain binding
might favor binding
might alter binding
might improve binding
might influence binding
might mediate binding
might provide binding
might generate binding
might involve binding
might detect binding
might think binding
might produce binding
might facilitate binding
might be binding
might allow binding
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