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The results contribute significantly to the understanding of how proteins might generate binding affinity and specificity independently, allowing promiscuous protein-protein interactions.
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The modular architecture of the IL-4-IL-4Rα interface suggests a possible mechanism by which proteins might be able to generate binding affinity and specificity independently.
Analyses of the modular architecture of the IL-4 – IL-4Rα interface yield a possible mechanism by which proteins might be able to generate binding affinity and specificity independently.
This leads to the question how proteins generate binding affinity and binding specificity [ 50].
Since members of the TGFβ superfamily transduce signals via a heterooligomeric receptor system, differences in binding affinities and specificities might generate a multiplicity of ligand-receptor complexes with different signaling properties, allowing cellular responses that differ in quality and quantity.
Honesty might generate trust.
These might generate 20percentt of the building's electricity.
It just might generate the groundswell of public support needed.
A hit movie might generate several hundred thousand sales.
A rumored sale of the division might generate $700 million.
You might generate that with a nuclear plant on board.
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