Sentence examples for microbial patterns in from inspiring English sources

The NOD proteins that recognize microbial patterns in the cytosol and endosomal TLRs do not exert such effects.

Knowledge of predominant microbial patterns in CAP constitutes the basis for initial decisions about empirical antimicrobial treatment [ 3].

A knowledge of the predominant microbial patterns in CAP is therefore essential when choosing an essential empirical antimicrobial treatment.

Knowledge of predominant microbial patterns in community-acquired pneumonia (CAP) constitutes the basis for initial decisions about empirical antimicrobial treatment, so a prospective study was performed during 2003 2004 among CAP of adult Chinese urban populations.

In the present work, we conducted a prospective study of the etiology of CAP in adult patients at 12 centers in 7 Chinese cities to assess the causative microbial spectrum, the influence of patient age, previous antibiotic use, and the Pneumonia Patient Outcomes Research Team PORTT) category of pneumonia on microbial patterns in the disease [ 4].

During infection, tissue-resident DCs recognize characteristic microbial patterns resulting in the uptake of pathogens, maturation and migration of DCs to lymphoid tissue, and activation of T-cell responses.

A study of the microbial patterns of CAP in patients aged ≥65 years found that S. pneumoniae was the most frequent pathogen in all age groups over 65 years and that age did not influence the microbial cause of CAP [ 6].

These clusters dominated by particular body habitats inferred that these body habitats harboured distinctive microbial patterns, which was also observed in base clustering results in Additional file 2: Figure S3.

Functioning either alone or in concert with specific co-receptors in recognizing microbial patterns the TLRs act as gate-keepers constantly sampling the environment and eliciting responses to prevent/control infection [ 15, 16].

This is achieved through recognition of conserved microbial patterns such as unmethylated CpG motifs in bacterial DNA [ 5], single-stranded or double-stranded (ds) viral RNA, lipopolysaccharide, peptidoglycan, and bacterial flagellin (for review, see [ 6]).

The importance of the interactions between pathogen-associated microbial patterns and mannose-binding lectin (MBL) in activating innate immunity has been considered as a component of the innate immune system [ 9].