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It was surprising, however, that IGF-1 levels in older Ghrl-/ mice were unchanged when compared to that of WT mice.

However, dystrophin RNA levels in the WT/mdx mice were unchanged relative to WT mice (Tables 2 and S2), even though WT/mdx mice contained only 10 30% of WT cells.

Levels of phospho-synapsin I and II in ethanol-treated AC1KO and DKO mice were unchanged from those of saline-treated WT and DKO controls (Figures 2 and 3).

Similarly, while WT and AC8KO mice demonstrated significant increases in eEF-2 phosphorylation in the hippocampus (Figure 4) and cortex (data not shown) following ethanol treatment compared to controls, levels of phospho-eEF-2 in DKO and AC1KO mice were unchanged from saline-treated controls (Figures 2 and 3).

Twelve days following intravenous injection of BiP into the RASM/SCID chimaeric mice, the histological features of the RASM taken from the control mice were unchanged compared with the markedly reduced cellular infiltrate in the RASM grafts from the BiP-treated mice.

Similar(55)

These alterations collectively contribute to an increase in the granule cell number in the DG of C57BL/6 MOR-1 KO mice, while the total number of granule cells in 129S6 MOR-1 KO mice is unchanged.

After treatment, the number of innervated synapses in treated and untreated mice was unchanged (Fig. 8B).

The insulin sensitivity estimated by ITT in HFD mice was unchanged in all treated groups.

Cumulative food intake of BACE1 −/− mice was unchanged compared with their WT littermates, whereas relative food intake was significantly higher.

Activation-based fluorescence in PBS-treated mice was unchanged in both of these experiments (Supplementary Figure  2).

The content of eNOS in muscles from nNOS Tg mice was unchanged compared with that seen in WT mice (Fig. 4B).

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