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Using 3D, time-lapse intravital imaging for direct visualization of the muscle regeneration process in live mice, we report that extracellular matrix remnants from injured skeletal muscle fibers, "ghost fibers," govern muscle stem/progenitor cell behaviors during proportional regeneration.

By using intracerebral inoculation of concentrated urine in cervid PrP transgenic mice, we report the presence of infectious prions in urine from CWD-infected cervids, and confirm the phenomenon of prionsialia in these animals.

In neonatal mice, we report that the PBf response to acidosis is abolished by pre-treatment with the SERT blocker fluoxetine and that SERT mRNA and 5-HT neurons are found in the vicinity of the RTN/pFRG area.

In α-syn transgenic mice, we report prominent mRNA downregulation of 14-3-3 14-3-3 14-3-3 θ in the cortex, a site of intense α-syn pathology.

Here, using LPCAT3-deficient cells and mice, we report that LPCAT3 is critical and relatively specific for the regulation of arachidonate levels in membrane phospholipids in vivo.

As proof of principle, Frech and coworkers [ 58] developed transgenic mice that overexpress ER-α in a C57BL/6 background, in which the number of ER-α positive cells in transfected glands was similar to that in the virgin BALB/c mice we report on here.

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In our maternally protein restricted mice we reported previously that PLP mice remained smaller throughout life whereas recuperated mice remained heavier than control animals throughout most of the adult life [32].

Using the PBP/MED1 liver conditional null (PBP/MED1ΔLiv) mice, we reported that PBP/MED1 is essential for liver regeneration and the peroxisome proliferator-activated receptor α ligand Wy-14,643-induced receptor-mediated hepatocarcinogenesis.

Using gpt delta transgenic mice, we reported recently that radiation can induce DNA damage and mutagenesis in the out of field lung and liver tissues after a 5 Gy dose of X-rays delivered to the lower abdomen of otherwise shielded animals.

The binary transgenic mouse we report here presents an opportunity for such measurements.

The differences between XXY and XY mice that we report could be the result of several genetic mechanisms that operate differently in mice with two vs. one X chromosome [ 60].

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