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The effect of ghrelin on GHRH neurons in aged (>22 months-old) male GHRH-GFP mice was indeed present but heterogeneous, being stimulatory in only 8 out of 13 experiments (supporting Figure S2C D).

Survival between lck-Cre and lck-Cre control mice was not different, demonstrating that the difference in survival between lck-Cre HIF-1 α loxP and lck-Cre HIF-1 α loxP mice was indeed due to Cre mediated HIF-1 α knock-down (data not shown).

The metabolic rate (resting metabolic rate, RMR) of Ate1-deficient mice was indeed higher than normal: they consumed on average 46.12 ml of O2 per kg per min, versus 29.3 ml of O2 per kg per min for Ate1-containing mice (Fig. 10E).

In order to further assess whether resistance to F-MLV-induced erythroleukemia in IDC-treated mice was indeed due to inhibition of early virus dissemination, and not to a toxic effect leading to reduction of target cells, we measured the direct effect of these compounds on erythroid differentiation in vivo.

Forced swim stress in mice was indeed found to increase c-fos activity in NPS-synthesizing neurons in the brain stem (Liu et al. 2011), implying that the NPS system may be stimulated upon stress exposure.

This analysis revealed that the percentage of Foxp3+ Treg cells within the CD4+ T cell population in the skin of DNFB-treated mice was indeed significantly increased compared with untreated mice, whereas total T cell populations remained unchanged (Fig. 2B).

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And the 'citation' that Cyagen asks for is nothing more than a mention in the methods section of a paper if Cyagen mice were indeed used for the experiment something that is already required by most journals, in part to assist in faithfully reproducing an experiment," Bohannon wrote.

If Eps8KO mice were indeed functionally calorie-restricted they should display increased longevity [7].

In the next experiment we verified that GluR2-cKO mice were indeed using an NMDAR-independent learning mechanism in context B (Fig. 8D).

In our study, mice were indeed protected by Lr32-pulsed BMDCs derived from IL-10 deficient mice, suggesting that the beneficial effect elicited by conditioned DCs is also independent of IL-10.

A stochastic model for XCI, involving an X-encoded XCI-activator, assumes that the nuclear volume is directly proportional to the ploidy, which in mice is indeed the case [45], [46].

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