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The infected mice did indeed do better than the uninfected ones.
Dr Yoshimoto showed that lowering DCA levels in mice did indeed reduce the development of liver cancer.Certain types of gut bacteria, including strains of Clostridium (a Gram-positive genus), are known to burp out DCA.
These mice did indeed lack several visual behaviours that are retained in the absence of rods and cones (circadian photoentrainment and photic suppression of wheel running activity), leading to the conclusion that together rods, cones and melanopsin account for all light detection in the mammalian retina[5].
Interestingly, when the daily high fat meal was not delivered, the female mice reacted by subtly increasing activity and food bin entry at expected meal time for two days, suggesting that these mice did indeed anticipate food arrival (or were entrained rhythmically) but did not express anticipatory activity or food bin entry.
However, despite demonstrating that aortic endothelial cells in plaque-laden areas from 9 month old ApoE−/− mice did indeed lack gap junctions, Yeh et al. [49] showed that adjacent plaque-free areas looked normal.
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First, she showed that mice do, indeed, respond to a high-protein diet in the way that people do.
Histological analysis also confirmed that the end-stage tumors induced by the various factors in mice do indeed resemble the human HCCs.
Telomerase knockout mice do indeed show a reduced formation of GC in the late-generation mice, most likely caused by the inability of lymphocytes to restore their telomere length in the GC (Herrera et al, 2000).
Our data demonstrate that aged transgenic AD mice do indeed spend more time in the open arm, a phenotype that was completely rescued by treatment with J147 for three months.
We found that the 1322T mouse did indeed develop more severe polyposis, with more tumours developing at a faster rate than in the Min model.
You could of course argue that mice are very different from people, but several of these genes did indeed directly overlap with genes linked to obesity in humans.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com