Sentence examples for mice the combination from inspiring English sources

Although both ERT and SRT monotherapies decreased DRG vacuolation relative to that seen in untreated mice, the combination of ERT and SRT produced the largest beneficial effect, decreasing vacuolation by ∼50%.

Hence, while immunization of mice with PspA3 conferred survival to only 30% of mice, the combination PspA3-wP induced 60% of survival (P = 0.007, when compared with non-immunized mice) (Table 5).

35, 36 In mice, the combination of specific mutations in the both Scn2a and Kcnq2 genes leads to more severe seizure phenotypes than either mutation individually.

In ob/ob mice, the combination of glucose overproduction and enhanced fatty acid synthesis was observed, leading to further increase of insulin secretion and resistance (McGarry 1992).

Considering that relatively low human-equivalent doses of ketoconazole were sufficient to increase 4-HPR systemic exposure in mice, the combination of 4-HPR and ketoconazole is expected to be well tolerated in patients.

For both subcutaneous and intracranial U87MG xenografted mice, the combination of F16 IL2 with temozolomide gave the best therapeutic results without additional toxicity, compared with the drugs as single agents (Supplementary Figure 2).

In addition, at least in mouse, the combination of IL-6 and transforming growth factor-β favours the Th17 pathway, but it has inhibitory effects on the function of regulatory T cells [ 19].

Everolimus effectively inhibited p-S6 but was not augmented by U0126., however, p-ERK was for the most part decreased however, some mice demonstrated resistance to U0126 However, mice receiving the combination therapy experienced a significant inhibition of ERK phosphorylation.

We observed that treatment of the mice with the combination of both human and mouse siRNA to ADMR greatly inhibited tumor growth and angiogenesis in vivo without obvious harmful effects.

Notably, the treatment of AML-bearing mice with the combination of AraC and CD82 mAb significantly prolonged their survival as compared with that of mice who received AraC alone (Fig. 2B).

Two mice on the combination regimen relapsed and achieved a second remission after a single dose of CD19L sTRAIL + TBI (Mouse #1: Remission 1: 19 days, Remission 2: 13 days; Mouse #2: Remission 1: 18 days, Remission 2: 12 days).