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A month later there were enough mice models to begin testing.

Studies were performed in WT, NPY−/−, nNOS−/− as well as NPY−/−/nNOS−/− double knock out mice models to understand the effects of absence of either NPY or nNOS in colonic inflammation.

Future directions include an ongoing validation study using patient-derived cell lines and mice models to improve drug prediction algorithms.

We performed xenograft mice models to investigate its therapeutic role in tumor genesis and metastasis in vivo.

Finally, in vivo testing was conducted in subcutaneous tumors grown on Balb/c mice models to evaluate the effect of our PDT treatment.

We then isolated total proteins from the hepatic fibrosis mice models to investigate the effect of β-sitosterol administration on the protein levels.

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Previous studies suggested the limitation of gene-modified mice model to solve this problem.

In the present study, we used the mice model to investigate anti-inflammation of EEDL.

We could find a few limitations in this mice model to evaluate the effect of ST.

We chose a nude mice model to generate a luciferase signal with less light attenuation for efficient optical bioluminescence imaging.

Alternatively, for agnostically discovered genes from GWAS, there is less concordance with mouse models to-date.

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