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Previous studies suggested the limitation of gene-modified mice model to solve this problem.

In contrast to wild-type FGF23, FGF23-21c gained the ability to activate FGFR1c and FGFR2c in the presence of βKlotho and was able to stimulate glucose uptake into adipocytes in vitro and lower glucose levels in ob/ob diabetic mice model to similar extent as FGF21 in vivo.

In the present study, we used the mice model to investigate anti-inflammation of EEDL.

We could find a few limitations in this mice model to evaluate the effect of ST.

We chose a nude mice model to generate a luciferase signal with less light attenuation for efficient optical bioluminescence imaging.

In this study, we established a type 2 DM mice model to mimic the progression of DN and evaluated the expression of TCP-1 β in the kidney.

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A month later there were enough mice models to begin testing.

We performed xenograft mice models to investigate its therapeutic role in tumor genesis and metastasis in vivo.

Objectives: To develop an ex-vivo mouse model to study the underlying mechanisms of hyperoxic vasoconstriction.

We specially designed a mouse model to further analyze the cofactor potential of these drugs.

Parkhurst et al. developed a mouse model to isolate CEA-reactive TCRs from splenocytes and perform functional assessment.

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