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This review examines recent developments in the animal modeling of glioma, from more established rat models to intriguing new systems using Drosophila and zebrafish that set the stage for higher throughput studies of potentially useful targets.
By manipulating cellular calcium or cAMP levels it is possible to stimulate cell proliferation and fluid secretion, and in mouse and rat models to affect disease severity.
This comparative genetics finding translated from mouse and rat models to human provided the first evidence of a causative role of ARNTL variants in the metabolic syndrome.
We confirmed these findings in I/R-induced AKI rat models to determine the underlying mechanism.
Zarbl's group uses rat models to search for genes associated with human breast cancer.
In the present study, we used two rat models to investigate mRNA translation in the liver following xenobiotic-induced toxicity.
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We established a chronic hypoxic rat model to confirm the effect of hypoxia on BMSCs.
Here we used a transgenic rat model to characterize ganglion cell responses to light and electrical stimulation during photoreceptor degeneration.
We developed a human fH transgenic infant rat model to investigate the effect of human fH on meningococcal bacteremia.
In this study, we used the tail-suspended, hindlimb unloading rat model to simulate the effects of microgravity.
The goal of this research is to use a rat model to investigate the behavioral/physiological consequences of chronic sleep restriction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com