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Combining imaging reporter viruses with genetically engineered reporter mice is expected to substantially enhance the power of bioluminescence imaging for quantitative studies of viral and host factors that control disease outcome and effects of established and new therapeutic agents.

Optimal ENU induction in mice is expected to lead to a mutation rate of approximately one mutation per 1.5 mega base pairs (Mbp) [14].

The average number of autosomal recombination events in DO mice is expected to increase linearly at a rate of 23.9 events per generation (Broman 2012).

In fact, the strong reduction of PV-positive cells observed in double KO mice is expected to correspond to a moderate reduction of the total CB-positive population of migrating precursors that include also other types of interneurons.

With this new insight into FCRL5 regulation, the development of genetically deficient mice is expected to enable a more systematic understanding of the in vivo physiology of the FCRLs and their fascinating properties in innate-like B cells.

Since PyVmT/Usp18 deficient cells are hypersensitive to type I IFN and, as we report here, type III IFN, delayed tumour onset in PyVmT/Usp18 KO mice is expected.

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Mice with genotype Erk1−/− Erk2fl/fl Tie2-Cre (Erk1−/− Erk2fl/fl Tie2-Cre to be born at a frequency of 12.5% fromicee initial breeding scheme employed (see Figure S1A for breeding schemes).

The Ctgf Lo/Lo mice are expected to have reduced Ctgf mRNA expression throughout the body.

HLA transgenic immunodeficient mice are expected to be useful for the generation of a good mouse model having human immunity.

S1PL activity in these S1PLH/− mice was expected to be lower than the enzyme activity in S1PLH/H mice.

In the F1 generation, 4 genotypes of mice were expected: wild type ; PGK-FLPo/+; GHRNeo/+ and GHRNeo/PGK-FLPo.

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