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Exact(29)
Complete Pten inactivation in mice is embryonic lethal.
It is well-established that complete Pten inactivation in Pten−/− mice is embryonic lethal.
Also, germline deletion of XBP1 [ 76] or IRE1α [ 128] in mice is embryonic lethal.
Interestingly, like VEGF, haploinsufficiency for the endothelial-specific Notch ligand Delta-like 4 in mice is embryonic lethal.
Genetic depletion of the calpain 4 small subunit in mice is embryonic lethal [8].
Knock out of palladin in mice is embryonic lethal at day 15.5[27].
Similar(31)
Furthermore, Ptc1 homozygous null mice are embryonic lethal suggesting that Ptc1 homozygous null mutations in humans are also incompatible with life [12].
Homozygous deletion of Ptc in the mouse was embryonic lethal.
Compared with the postnatal lethality of STX-T-deficiency mice, TFR-deficiency mice are embryonic lethal before E12.5 with anemia (Levy et al., 1999).
For instance, MEK1 knockout mice are embryonic lethal [17].
Hdac7 null mice are embryonic lethal and die at E11.0.
Related(20)
mice is cell
mice is unlikely
mice is indistinguishable
mice is comparable
mice is uncertain
mice is absent
mice is dependent
mice is difficult
mice is consistent
mice is due
mice is indicative
mice is critical
mice is distinct
mice is sufficient
mice is compatible
mice is unclear
mice is low
mice is important
mice is different
mice is abnormal
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