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Furthermore, the decrease in Hsp70 in the CR mice is indicative of increased apoptosis, since the presence of Hsp prevents the recruitment of caspase 9 to the apoptosome [81].
Marginal zone B cells were reduced only by half upon treatment, which compared to their almost complete absence observed in BAFF and BAFF-R deficient mice, is indicative for a crucial role of BAFF signaling during marginal zone B cell development or survival of their progeny, but dispensable for their survival subsequent to maturation.
Deficiency in the intrasession habituation of Bmal1-/ mice is indicative for working memory impairments.
The observed thickening of the SC in TCDD-exposed mice is indicative of a pronounced epidermal hyperkeratosis.
The preponderance of cardiomyocytes in early and late apoptosis in tamoxifen-treated αMHC-MerCreMer mice is indicative of Cre-induced apoptosis.
Because of the much greater affinity of the C4F6 antibody for the G93A protein, we cannot be sure whether the immunoreactivity detected in these mice is indicative of conformational change.
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The significant HIV-1 specific proliferative CD4+ T cell responses in immunized mice was indicative of the magnitude of the T helper activity elicited by HIVBr18.
Body weight and temperature changes of test mice were indicative illness and mice vaccinated with high-dose VLP and whole virus vaccine returned to their original weight by day 13 post-challenge (Fig. 8C, D), a result consistent with the survival outcome.
As shown in Fig. 6A and C, although the difference between control-naive (n = 20) and tg-naïve (n = 20) mice in ACTH (83.1 vs. 59.6 pg/ml; p = 0.0735) or CORT (54.5 vs. 39.9 ng/ml; p = 0.0620) did not reach a significant level, a tendency of a lower basal level of the HPA axis activity in tg mice was indicative.
The p values of these slopes (i.e. whether they are significantly above 0) are collected, transformed (1/average –Logp, see materials and methods) and used to determine whether the response of the mice are indicative of degrees of susceptibility (Saai) or resistance (Raai).
Indeed, the present data from GluN1hypo mice are indicative of a global impairment rather than any specific disease.
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