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In the present study, we confirmed that BALB/C mice are sensitive to ADR-induced nephropathy, while C57BL/6 mice are resistant to such damage.
Thus Leptin145E/145E mice are sensitive to the exogenous administration of wild-type leptin, suggesting the mutant V145E leptin is not functional.
Using a new approach to compare whether animals are resistant or have varying degrees of susceptibility to developing allergic airway inflammation, we demonstrate that both strains of mice are sensitive to developing allergic airway inflammation, but that C57BL/6 mice are less susceptible than BALB/c mice.
Previously Kuida et al demonstrated a caspase-9 dependent and caspase-3 independent apoptotic pathway, since thymocytes from caspase-9-/ mice are resistant to gamma irradiation and dexamethasone, whereas thymocytes from caspase-3-/ mice are sensitive, suggesting that other caspases are directly activated by caspase-9 [43].
Rats and mice are sensitive to hepatocellular hyperplastic effects of PPARα ligands.
In fact, Il4 gene knockout mice are sensitive to RANKL-induced bone resorption [ 61].
Similar(39)
Taken together, these data reveal that synaptic protection in the CNS of WldS mice is sensitive to gene-dose.
As shown in Figure 2, the AG129 mice were sensitive to the virus at varying degrees based on the viral inoculum, with disease progressing slowly and animals first succumbing on day 10 of infection.
Moreover, tumours from these mice were sensitive to MEK inhibition.
Aachoui et al. revealed that the caspase-11 knockout mice were sensitive to infection by cytosolic bacteria, but resistant to LPS sepsis.
These mice were sensitive to CCl4-induced liver injury and displayed increased levels of hepatic necrosis (Fig. 5H K) with significant morbidity occurring within 2 weeks (Fig. 5L).
Related(20)
birds are sensitive
individuals are sensitive
mice are responsive
mice are critical
mice are significant
ones are sensitive
squirrels are sensitive
mice are susceptible
mice are vulnerable
studies are sensitive
mice are sensitized
mice are inescapable
mice are able
mice are prolific
mice are nocturnal
mice are small
mice are great
mice are black
mice are resistant
mice are abnormal
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