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The methodological details such as grouping human CpG-poor and CpG-rich promoters are described in the Methods.
Bibliographic data were noted for each study, as were methodological details such as sample, control or comparison and intervention components (Table 1).
Key information could be missing including the rationale for undertaking the qualitative research and methodological details such as sample size and approach to analysis.
However, reviewers may need to examine many other methodological details such duration of trial, follow up period, secondary outcomes such as adverse events, toxicity, and side effects, or statistical computations such as odds ratios, hazard ratios, and so on.
This appears to reflect a lack of shared understanding on methodological details, such as how more 'meaningful' data categories and measures might best be developed to improve causal understanding or the targeting of interventions.
Comparing the results of different allergen challenge studies requires caution, as methodological details such as the period of measurement of the late response can vary between studies (we measured up to 10 hours while some studies only measure up to 7 hours), and individual patient characteristics may differ.
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9 15 Although methodological details vary, such follow-up studies focus on patient populations, defined according to the cause, severity and other characteristics of their injuries.
Recommendations of this nature are important since they require reporting of methodological details not addressed by generic standards such as CONSORT [ 21].
Although several limitations of prior studies were identified such as small sample sizes and lack of methodological details, findings overall suggest that mindfulness training may be an effective treatment for addictions.
However, it is just these methodological details that allow investigators to reproduce experiments of others and to understand how important variables such as sex or hormonal status may influence outcomes.
The ethical codes of organizations like the American Association for Public Opinion Research mandate the disclosure of these sorts of methodological details upon request.
Related(20)
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Justyna Jupowicz-Kozak
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