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Exact(5)

This method cannot find solutions in concave parts of the Pareto front.

It is also clear that a single-condition method cannot find the differential edges correctly and has the worst performance.

If the solution method cannot find the whole Pareto front within the 3 day budget, we report " > 3 d " for CPU time.

This method cannot find out all the causes of AEs, as reviewers are dependent on information written down in the patient records [ 28].

If it is just to show that the proposed method cannot find any prognostic markers for the carcinomas considered, I do not see why it is interesting.

Similar(55)

In other word, these methods cannot find low-degree essential proteins.

As can be seen in Table 3, while the other methods cannot find junctions with unknown motifs, PASSion detects 78 junctions in this category (one example is shown in the Supplementary Fig. S4).

Many of the putative, novel retrogenes, potentially encoding proteins with no similarities to other existing proteins, may have been missed by methods relying on protein alignments, as protein-based screening methods cannot find antisense insertions and also are not able to align UTR regions of retrogenes.

Furthermore, this method cannot exhaustively find all non-repetitive W contigs – it can only detect unique regions specific to the W. Sequences in the pseudoautosomal region will produce the same read depth as autosomal regions, and recent gene duplication events may produce W-linked sequences with enough similarity to autosomal or Z-linked sequence to be represented in male genomes.

However, the main drawback of this method is that it cannot find species-specific regulatory elements.

Note that the biologically interpretable TF knockout targets (identified by our method) cannot be found by simply intersecting the TFKM data with the ChIP-chip data since the overlap is very low (see Figure 3).

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