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More interestingly, we demonstrate the ability of this cholinesterase inhibitor to improve the memory deficit observed in cirrhotic rats.
This means the spatial memory deficit observed in water maze test was not due to the motor dysfunction after thrombin injection.
Importantly, CDPPB sub-chronic treatment ameliorated HD-related memory deficit observed in BACHD mice, further emphasizing mGluR5 PAMs' potential as drugs to treat neurodegenerative diseases, especially HD.
A replication of the memory deficit observed in Experiment 1 in subclinically depressed participants would confirm that dysphoric mood influences memory for pictorial material and verbal material similarly.
In order to further dissect the memory deficit observed during the initial MWM experiments (Halt et al., 2012), two independent cohorts of GluN2B KI mice and their WT littermate controls (10 mice of each genotype per cohort) underwent a massed training protocol on a single day in the MWM.
As fRIM1/KA-cre+ mice lack RIM1 robustly in area CA3 and mosaically in the DG, it raises the possibility that the learning and memory deficit observed in RIM1 α−/− mice may be due, at least in part, to the loss of RIM1 from extra-hippocampal synapses and may or may not require a loss of RIM1 in the hippocampus.
Similar(54)
Different lesions are applied to the model in order to investigate the working memory deficits observed in Parkinson's disease and schizophrenia.
They also predict that the working memory deficits observed in schizophrenia involve many cortical and subcortical areas and result from a problem in selecting items in working memory which are stored in basal ganglia-thalamocortical loops.
The simulations predict that the working memory deficits observed in Parkinson's disease result from a local dysfunction within the brain due to a problem in the disinhibitory process arising from the basal ganglia.
The data show that neuronal cytoarchitectural changes are long-lasting following developmental MDMA exposure and are in regions consistent with the learning and memory deficits observed in such animals.
Here, we investigate whether this framework can account for memory deficits observed following right or left temporal lobe damage, as suggested by Blaxton and Theodore [Brain and Cognition 35 (1997) 5].
Related(16)
memory defect observed
recollection deficit observed
memory impairment observed
memory deficit was
memory deficit were
memory effect observed
memory deficit found
memory function observed
memory decline observed
memory profile observed
memory pattern observed
memory enhancement observed
memory system observed
memory behavior observed
memory disturbance observed
memory deficit evident
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Justyna Jupowicz-Kozak
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