Sentence examples for membrane potential due from inspiring English sources

The fundamental difference with respect to apoptosis is the rapid loss of cellular membrane potential due to energy depletion and ion pump/channel failure, leading to swelling and cytolysis.

To experimentally eliminate variation in membrane potential due to recent synaptic activity, additional whole-dish probing periods were conducted, in the presence of fast synaptic receptor blockers, before and after the patterned stimulation protocols (Fig. 5A), and long-term plasticity of action potential propagation delay and amplitude persisted (Fig. 5B).

To verify the functional linkage of these proteins with the ETC we blocked the electron flow of the oxidative phosphorylation chain using piericidin A, a selective inhibitor of NDH (Complex I) [30] where 90% of the membrane potential due to the redox reaction of complex I activity has previously been shown to be inhibited in E. coli [31], [32].

However, possible changes in plasma membrane potential due to FCCP-induced effects including potential shortage in ATP are ignored.

One of the earliest changes occurring after P2X7R activation is the collapse of plasma membrane potential due to Na+ influx.

We originally hypothesized that this would lead to greater mitochondrial membrane potential due to the increase in electron transport activity and perhaps also a higher cellular ATP.

Importantly, fusiform cell hyperactivity in tinnitus mice is associated with reduced KCNQ2/3 currents at hyperpolarized membrane potentials, due to a depolarizing shift in the voltage dependence of KCNQ2/3 channel opening (Li et al., 2013).

Spontaneous activity was obtained by introducing a randomly distributed stimulation reproducing the effect of fluctuation in the membrane potential [33] due to the distributed background activity.

However, since VCP has also been shown to be recruited directly to damaged mitochondria (Kim et al., 2013) we cannot rule out the possibility that the effects on mitochondrial morphology and membrane potential are due to direct VCP functions at the mitochondrial outer membrane.

A decrease in the basal membrane potential Vbp due to the presence of an anion channel would provide an increase in the transepithelial potential Vtp, The Cl− flow through the junction contacts [ 31, 33], which are more permeable for anions than for cations [ 63, 64], would activate the cycling of Na+ counter-ions through the epithelium and along the midgut and haemolymph [ 60].

Depolarisation of the membrane potential may be due to increased radical production promoted by NPs themselves, and oxidation of cardiolipin causes the release cytochrome c.