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However, for absorbing receivers [94], which in relation to cellular activities mimic information transfer through membrane diffusion and endocytosis/exocytosis processes, the model has to be modified to account for information molecules detection and removal from the propagation environment.
Membrane diffusion and penetration studies were completed as well for each formulation in vitro and ex vivo, followed by measurements on skin hydration and transepidermal water loss in vivo.
These results suggested no major defects in membrane diffusion and traffic of Bgs4, although some internal accumulation was observed in cdc42L160S cells.
We investigated the influence of β-arrestin adaptors and endocytosis mechanisms on plasma membrane diffusion and particle brightness of GFP-tagged neuropeptide Y (NPY) receptors.
For example, the zwitterionic nature of the pharmacophore may impose limitations on passive membrane diffusion and, similar to other BCL-2 family inhibitors, A-1210477 and related analogs are highly protein bound.
These techniques have been successfully applied in cells to study the plasma membrane diffusion and oligomeric state of GPCRs tagged with variants of green fluorescent protein (GFP) [17 21], and to monitor the binding of fluorescent GPCR ligands [17,22,23].
Similar(53)
This study sheds light on the formation and lipid composition of the nuclear and ER membrane diffusion barrier, and shows that misfolded and presumably aggregated proteins are also asymmetrically retained within the mother cell.
These include complex interrelationships between lumen and membrane diffusion, convection, degradation and absorption mechanisms — and overall axial convection, dispersion, degradation and absorption rates.
A two-dimensional model has been used to simulate the oxidative dehydrogenation of butane on a two-layer catalytic membrane (diffusion layer and V/MgO active layer) operating with segregated reactant feeds.
We have so far neglected possible membrane diffusion of receptors and ligands, potential targeting of newly synthesised EGFR and ligand to, or clustering at, stable E-cadherin-mediated contacts.
Filamentous septin assemblies act as scaffolds and membrane diffusion barriers to modify membrane properties and restrict in space and time the localization of other proteins (Oh and Bi 2011).
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