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Aconitase allows the TCA cycle to function during periods of oxidative stress, and may play a role in mediating oxidative stress and regulating cell death [53], [76].
Here we discuss the role of Nox4 in mediating oxidative stress in mitochondria and during aging in the heart.
Transforming growth factor (TGF -β has been exTGF -βely reported to be involved in mediating oxidative stress induced premature senescence of fibroblasts [ 17- 19].
In this work, we take advantage of a recently characterized transposable element insertion mediating oxidative stress response in Drosophila melanogaster to test the dominance effect of an adaptive mutation.
Subsequently, we examined the up-regulation or uniquely expressed genes following amended medium treatment, which were also expressed on the enrichment pathway, and found that most of them participated in mediating oxidative stress homeostasis.
For SodB that has been identified as a factor in F. tularensis oxidative stress protection [ 71], we found multiple potential interacting partners, including interactions with the murine thioredoxin-interacting protein Txnip, a protein mediating oxidative stress via thioredoxin activity [ 72].
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Another finding suggests that the MAPK11/12/13/14 pathway participates in mediating oxidative stress-induced autophagy-related genes such as ATG7.
For example, Azevedo et al. [ 24] showed that rutin and quercetin prevented thermal and mechanical nociceptive responses in oxaliplatin-induced neuropathic pain in mice by mediating oxidative stress-induced damage.
This model is consistent with an important role of CypD (Baines et al, 2005; Nakagawa et al, 2005) in mediating oxidative stress-induced mitochondrial permeability transition (Hua et al, 2007; Montesano Gesualdi et al, 2007), a cell death response antagonised by mitochondrial Hsp90s (Kang et al, 2007).
Hexavalent chromium-mediated oxidative stress causes severe organ damage.
On the whole, these observations indicate that AWW has an ameliorative effect on crude oil mediated oxidative stress.
Related(19)
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facilitating oxidative stress
mitigating oxidative stress
alleviating oxidative stress
mediated oxidative stress
mediate oxidative stress
mediating cellular stress
mediating environmental stress
mediating cold stress
mediating early stress
mediating benzoate stress
mediating oxidative injury
mediating oxidative damage
mediating various stress
mediating basic stress
mediating osmotic stress
mediating mechanical stress
mediating abiotic stress
mediating several stress
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